The growing threat of antimicrobial resistance has led researchers to search for new compounds everywhere, according to a famotsorana vaovao issued by the American Society for Microbiology. This week in mBio, a multinational team of researchers in Europe report the discovery of a new antifungal antibiotic named solanimycin.
The compound, initially isolated from a pathogenic bacterium that infects potatoes, Dickeya solani, appears to be produced by a broad spectrum of related plant pathogenic bacteria.
Solanimycin acts against a wide range of fungi known to infect and wreak havoc on agricultural voly, according to the researchers. In lab studies, the compound also acted against Candida albicans, a fungus that occurs naturally in the body but can cause dangerous infections. The results suggest that solanimycin, and related compounds, could be useful in both agricultural and clinical settings.
Ny mikraoba amin'ny tany, indrindra fa avy amin'ny phylum Actinobacteria, dia mamokatra ny ankamaroan'ny antibiotika fitsaboana ampiasaina ankehitriny. Ny fikarohana vaovao dia manoro hevitra fa ny zavamiaina bitika dia tokony hojerena akaiky, indrindra fa ny vokatra dia mampitombo ny fanoherana ny fitsaboana efa misy, hoy i Rita Monson, Ph.D., manam-pahaizana momba ny microbiologie, ao amin'ny Oniversiten'i Cambridge. Niara-nitarika ny fianarana niaraka tamin'i Miguel Matilla, Ph.D., manam-pahaizana momba ny molekiola, ao amin'ny Estación Experimental del Zaidín, ao amin'ny Filankevitry ny Fikarohana Espaniola, any Granada izy.
Ny bakteria pathogenic ovy Dickeya solani, which produces solanimycin, was first identified more than 15 years ago. Researchers in the lab of molecular microbiologist George Salmond, Ph.D., at the University of Cambridge, began investigating its antibiotic potential about a decade ago.